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Selected Publications

Khazen T, Hatoum OA, Ferreira G, Maroun M. 2019. Acute exposure to a high-fat diet in juvenile male rats disrupts hippocampal-dependent memory and plasticity through glucocorticoids. Sci. Rep. 9(1):


Khazen T, Shrivastava K, Jada R, Hatoum OA, Maroun M. 2018. Different mechanisms underlie stress-induced changes in plasticity and metaplasticity in the prefrontal cortex of juvenile and adult animals: Emotional-induced metaplasticity in the prefrontal cortex. Neurobiol. Learn. Mem.


Yaseen A, Shrivastava K, Zuri Z, Hatoum OA, Maroun M. 2018. Prefrontal Oxytocin is Involved in Impairments in Prefrontal Plasticity and Social Memory Following Acute Exposure to High Fat Diet in Juvenile Animals. Cereb. Cortex


Cohen L, Maroun M, Wagner S. 2018. Behavior: Oxytocin Promotes Fearless Motherhood. Curr. Biol. 28(8):R359–61


Saha R, Shrivastava K, Jing L, Schayek R, Maroun M, et al. 2018. Perturbation of GABAergic Synapses at the Axon Initial Segment of Basolateral Amygdala Induces Trans-regional Metaplasticity at the Medial Prefrontal Cortex. Cereb. cortex (New York, N.Y. 1991). 28(1):395–410


Schayek R, Maroun M. 2017. Dissociation in the effects of stress and D1 receptors activation on basolateral amygdalar LTP in juvenile and adult animals. Neuropharmacology. 113(Pt A):511–18


Kritman M, Lahoud N, Maroun M. 2017. Oxytocin in the amygdala and not the prefrontal cortex enhances fear and impairs extinction in the juvenile rat. Neurobiol. Learn. Mem. 141:179–88


Levin N, Kritman M, Maroun M, Akirav I. 2017. Differential roles of the infralimbic and prelimbic areas of the prefrontal cortex in reconsolidation of a traumatic memory. Eur. Neuropsychopharmacol. 27(9):900–912


Kritman M, Maroun M. 2017. Toward Comprehensive Understanding of the Effects of Intranasal Oxytocin on the Human Amygdala. Biol. Psychiatry. 82(12):864–65


Brill-Maoz N, Maroun M. 2016. Extinction of fear is facilitated by social presence: Synergism with prefrontal oxytocin. Psychoneuroendocrinology. 66:75–81


Slouzkey I, Maroun M. 2016. PI3-kinase cascade has a differential role in acquisition and extinction of conditioned fear memory in juvenile and adult rats. Learn. Mem. 23(12):723–31


Maroun M, Wagner S. 2016. Oxytocin and Memory of Emotional Stimuli: Some Dance to Remember, Some Dance to Forget. Biol. Psychiatry. 79(3):203–12


Moench KM, Maroun M, Kavushansky A, Wellman C. 2015. Alterations in neuronal morphology in infralimbic cortex predict resistance to fear extinction following acute stress. Neurobiol. Stress. 3:23–33


Schayek R, Maroun M. 2015. Differences in stress-induced changes in extinction and prefrontal plasticity in postweanling and adult animals. Biol. Psychiatry. 78(3):159–66


Awad W, Ferreira G, Maroun M. 2015. Dissociation of the Role of Infralimbic Cortex in Learning and Consolidation of Extinction of Recent and Remote Aversion Memory. Neuropsychopharmacology. 40(11):2566–75


Boitard C, Maroun M, Tantot F, Cavaroc A, Sauvant J, et al. 2015. Juvenile obesity enhances emotional memory and amygdala plasticity through glucocorticoids. J. Neurosci. 35(9):4092–4103


Herman JP, Maroun M, Richter-Levin G. 2015. Good stress, bad stress and very bad stress. Stress. 18(3):267–68


Maroun M, Wagner S. 2015. Oxytocin and memory of emotional stimuli: some dance to remember, some dance to forget. Biol. Psychiatry


Motanis H, Maroun M, Barkai E. 2014. Learning-induced bidirectional plasticity of intrinsic neuronal excitability reflects the valence of the outcome. Cereb. cortex (New York, N.Y. 1991). 24(4):1075–87


Kritman M, Richter-Levin G, Maroun M. 2014. The role of Corticotropin-releasing hormone signaling in the extinction of conditioned fear across development. J. Mol. Neurosci. 53:S73–74


Lahoud N, Maroun M. 2013. Oxytocinergic manipulations in corticolimbic circuit differentially affect fear acquisition and extinction. Psychoneuroendocrinology. 38(10):2184–95


Kritman M, Maroun M. 2013. Inhibition of the PI3 kinase cascade in corticolimbic circuit: temporal and differential effects on contextual fear and extinction. Int. J. Neuropsychopharmacol. 16(4):825–33


Slouzkey I, Rosenblum K, Maroun M. 2013. Memory of conditioned taste aversion is erased by inhibition of PI3K in the insular cortex. Neuropsychopharmacology. 38(7):1143–53


Shehadi K, Maroun M. 2013. Different effects of low frequency stimulation to infralimbic prefrontal cortex on extinction of aversive memories. Brain Res. 1490:111–16


Wellman CL, Camp M, Jones VM, MacPherson KP, Ihne J, et al. 2013. Convergent effects of mouse Pet-1 deletion and human PET-1 variation on amygdala fear and threat processing. Exp. Neurol. 250:260–69


Kavushansky A, Kritman M, Maroun M, Klein E, Richter-Levin G, et al. 2013. Beta-Endorphin Degradation and the Individual Reactivity to Traumatic Stress. Eur. Neuropsychopharmacol. 23(12):1779–88


Akirav I, Maroun M. 2013. Stress modulation of reconsolidation. Psychopharmacology (Berl). 226(4):747–61


Maroun M. 2013. Medial prefrontal cortex: multiple roles in fear and extinction. Neuroscientist. 19(4):370–83


Schmidt M V, Abraham WC, Maroun M, Stork O, Richter-Levin G. 2013. Stress-induced metaplasticity: from synapses to behavior. Neuroscience. 250:112–20


Maroun M, Ioannides PJ, Bergman KL, Kavushansky A, Holmes A, Wellman CL. 2013. Fear extinction deficits following acute stress associate with increased spine density and dendritic retraction in basolateral amygdala neurons. Eur. J. Neurosci. 38(4):2611–20


Maroun M, Kavushansky A, Holmes A, Wellman C, Motanis H. 2012. Enhanced extinction of aversive memories by high-frequency stimulation of the rat infralimbic cortex. PLoS One. 7(5):e35853


Motanis H, Maroun M. 2012. Differential involvement of protein synthesis and actin rearrangement in the reacquisition of contextual fear conditioning. Hippocampus. 22(3):494–500


Vouimba R-M, Maroun M. 2011. Learning-induced changes in mPFC-BLA connections after fear conditioning, extinction, and reinstatement of fear. Neuropsychopharmacology. 36(11):2276–85


Vouimba RM, Maroun M. 2011. Learning-induced changes in mPFC-BLA connections after fear conditioning, extinction, and reinstatement of fear. Neuropsychopharmacology. 36(11):2276–85


Cohen Y, Avramoav S, Barkai E, Maroun M. 2011. Olfactory learning-induced enhancement of the predisposition for LTP induction. Learn. Mem. 18(9):594–97


Motanis H, Maroun M. 2010. Exposure to a novel context following contextual fear conditioning enhances the induction of hippocampal long-term potentiation. Eur. J. Neurosci. 32(5):840–46


Richter-Levin G, Maroun M. 2010. Stress and amygdala suppression of metaplasticity in the medial prefrontal cortex. Cereb. cortex (New York, N.Y. 1991). 20(10):2433–41


Motanis H, Maroun M. 2010. Exposure to a novel context following contextual fear conditioning enhances the induction of hippocampal long-term potentiation. Eur. J. Neurosci. 32(5):840–46


Akirav I, Segev A, Motanis H, Maroun M. 2009. D-Cycloserine into the BLA reverses the impairing effects of exposure to stress on the extinction of contextual fear, but not conditioned taste aversion. Learn. Mem. 16(11):682–86


Maroun M, Akirav I. 2009. Differential involvement of dopamine D1 receptor and MEK signaling pathway in the ventromedial prefrontal cortex in consolidation and reconsolidation of recognition memory. Learn. Mem. 16(4):243–47


Maroun M, Akirav I. 2008. Arousal and stress effects on consolidation and reconsolidation of recognition memory. Neuropsychopharmacology. 33(2):394–405


Yarom O, Maroun M, Richter-Levin G. 2008. Exposure to forced swim stress alters local circuit activity and plasticity in the dentate gyrus of the hippocampus. Neural Plast. 2008:194097


Cohen Y, Reuveni I, Barkai E, Maroun M. 2008. Olfactory learning-induced long-lasting enhancement of descending and ascending synaptic transmission to the piriform cortex. J. Neurosci. 28(26):6664–69


Hikind N, Maroun M. 2008. Microinfusion of the D1 receptor antagonist, SCH23390 into the IL but not the BLA impairs consolidation of extinction of auditory fear conditioning. Neurobiol. Learn. Mem.



Belelovsky K, Maroun M, Rosenblum K. 2007. MAPK activation in the hippocampus in vivo is correlated with experimental setting. Neurobiol. Learn. Mem. 88(1):58–64


Akirav I, Maroun M. 2007. The role of the medial prefrontal cortex-amygdala circuit in stress effects on the extinction of fear. Neural Plast. 2007:30873


Akirav I, Khatsrinov V, Vouimba RM, Merhav M, Ferreira G, et al. 2006. Extinction of conditioned taste aversion depends on functional protein synthesis but not on NMDA receptor activation in the ventromedial prefrontal cortex. Learn. Mem. 13(3):254–58


Akirav I, Raizel H, Maroun M. 2006. Enhancement of conditioned fear extinction by infusion of the GABA(A) agonist muscimol into the rat prefrontal cortex and amygdala. Eur. J. Neurosci. 23(3):758–64


Maroun M. 2006. Stress reverses plasticity in the pathway projecting from the ventromedial prefrontal cortex to the basolateral amygdala. Eur. J. Neurosci. 24(10):2917–22


Akirav I, Maroun M. 2006. Ventromedial prefrontal cortex is obligatory for consolidation and reconsolidation of object recognition memory. Cereb. cortex (New York, N.Y. 1991). 16(12):1759–65


Maroun M, Delelis O, Coadou G, Bader T, Segeral E, et al. 2006. Inhibition of early steps of HIV-1 replication by SNF5/Ini1. J. Biol. Chem. 281(32):22736–43


Maroun M, Richter-Levin G. 2003. Exposure to acute stress blocks the induction of long-term potentiation of the amygdala-prefrontal cortex pathway in vivo. J. Neurosci. 23(11):4406–9


Genin A, French P, Doyere V, Davis S, Errington ML, et al. 2003. LTP but not seizure is associated with up‐regulation of AKAP‐150. Eur. J. Neurosci. 17(2):331–40


Maroun M, Richter-Levin G. 2002. Local circuit plasticity in the rat dentate gyrus: characterization and aging-related impairment. Neuroscience. 112(4):1001–7


Stewart MG, Harrison E, Rusakov DA, Richter-Levin G, Maroun M. 2000. Re-structuring of synapses 24 hours after induction of long-term potentiation in the dentate gyrus of the rat hippocampus in vivo. Neuroscience. 100(2):221–27


Rosenblum K, Maroun M, Richter-Levin G. 1999. Frequency-dependent inhibition in the dentate gyrus is attenuated by the NMDA receptor blocker MK-801 at doses that do not yet affect long-term potentiation. Hippocampus. 9(5):491–94


Leshem M, Maroun M, Weintraub Z. 1998. Neonatal diuretic therapy may not alter Children’s preference for salt taste. Appetite. 30(1):53–64


Leshem M, Maroun M, Del Canho S. 1996. Sodium depletion and maternal separation in the suckling rat increase its salt intake when adult. Physiol. Behav. 59(1):199–204